1. This site uses cookies. By continuing to use this site, you are agreeing to our use of cookies. Learn More.

"Extreme Skewing of X Chromosome Inactivation in Mothers of Homosexual Men"

Discussion in 'Current Events, World News, & LGBT News' started by Hoppip, Jan 2, 2010.

  1. Hoppip

    Full Member

    Joined:
    May 27, 2008
    Messages:
    838
    Likes Received:
    0
    Location:
    Johto
    (Thank you citation button!)

    While I was cruising through the online academic reference site to the University of California at Los Angeles, I found this research paper that shows promise to the nature-nurture debate on howmowsexuality. With the help of Vic's biochemistry genius and CONTEXT CLUES I was able to pull together its basic idea:

    1. Women have two X chromosomes, but each cell only needs one to function, therefore each cell randomly "deactivates" one of the X chromosomes.
    2. Theoretically, each cell in the female body would have a 50/50 chance of having either an activated or deactivated X chromosome.
    3. Realistically, this isn't the case, and each woman has a variance in the amount of cells that use either X chromosome.
    4. Mothers of heterosexual men had around a 4% skew of inactivation, whereas mothers of homosexual men had around a 13% skew of inactivation.

    It's also important to note, says the paper, that the X chromosome influences sex, reproduction, and cognition (wait... duh.).

    I thought I might bring this little jewel to you, of EC, and see your thoughts perhaps? I would assume that this paper doesn't prove causation but correlation. I think it's actually a very interesting discovery especially since the "selective abortion" argument couldn't work here because it's part of the mother and not the fetus (unless you argue that the fetal chromosomes could be analyzed, so nevermind).

    Thoughts?
     
  2. Just Adam

    Full Member

    Joined:
    Mar 17, 2009
    Messages:
    4,435
    Likes Received:
    1
    Location:
    My AV room
    i think its a horrid thing to start saying in teh scientific community that homosexuals are teh result of some genetic skew... like we are some genetic fuck up.

    i think if anythign this only helps fuel teh argument that homosexuals are some mistake :frowning2:

    my mother wouldent say im a mistake. well then again i dunno if she knew maybe dissown me...i vaugely remember her talking about when i grow up and find a woman or summat.

    but yea anyway i dont care for this thanks for bringing it to the table though.
     
  3. olides84

    Full Member

    Joined:
    Jun 5, 2008
    Messages:
    953
    Likes Received:
    0
    Location:
    Belgium
    I don't think that at all. 'Variation' is a better way to think about it - just like hair color, handedness, etc. And when you start scientifically identifying biological or 'natural' reasons for homosexuality, it blunts the "it's a choice" bullshit arguments.
     
  4. starfish

    Full Member

    Joined:
    Nov 11, 2008
    Messages:
    3,368
    Likes Received:
    0
    Location:
    Hippie Town, Alberta of the US
    2 Things. First it is spelt THE not TEH.

    Second every living creature, from the lowest virus to humans is the result of genetic fuck ups. Though as olides84 pointed out, the proper term is variance. Variance is the driving force behind evolution and natural selection.
     
  5. kettleoffish

    Full Member

    Joined:
    Feb 20, 2009
    Messages:
    891
    Likes Received:
    0
    Location:
    Scotland
    I don't normally like to nitpick, but is there any chance you could, like, type slower, or check your posts before hitting submit? I've noticed quite often that half of what you say is indiscernible, and I think people might pay attention to your posts a bit more if they could read them :slight_smile:

    As has been said, everything that makes anyone different from anyone else is the result of 'genetic fuck ups', if there wasn't variation we'd all be the exact same. the scientific community doesn't tend to (or like to) involve themselves with moral debate and because of this, sometimes the wording used can come across as offensive. Remember that 'disorder' in a scientific context means something quite different to in a sociological context. It isn't intended to have any negative (or positive) connotations, just states difference.
     
  6. Just Adam

    Full Member

    Joined:
    Mar 17, 2009
    Messages:
    4,435
    Likes Received:
    1
    Location:
    My AV room
    ffs pick pick pick...ill just not bother. make everyone happy. i think the idea of me beeing the result of something skewd sucks.

    hope thats clear enough.
     
  7. kettleoffish

    Full Member

    Joined:
    Feb 20, 2009
    Messages:
    891
    Likes Received:
    0
    Location:
    Scotland
    sorry.. I wasn't trying to be offensive, I've always liked your points of view, I was just trying to make it so more people could read what you wrote too :slight_smile:
     
  8. Stephen505

    Regular Member

    Joined:
    Dec 29, 2009
    Messages:
    26
    Likes Received:
    0
    Location:
    Toronto, ON
    Gender:
    Male
    Sexual Orientation:
    Gay
    Out Status:
    Out to everyone
    Tbh, I know basically nothing about the original topic here.. But to talk about this little debate a bit:

    ASSUMING that the original topic holds some truth, saying that would not be very different than talking about people with blonde hair and stuff. It isn't like saying: "oh your genes are broken, you've given birth to a mutant", it's more like saying: "there's a LOW CHANCE that your child will be born with this certain trait, the chances are higher depending on your genes".

    As an analogy (which may be a bit wrong, again, I don't know much about this skew chromosome stuff..): I could say: there's a low chance you will give birth to a child with a recessive trait, but if both parents carry the recessive trait the probability is higher, AND if both parents exhibit the recessive trait, the probability is almost certain.

    On the other hand, I would say: there's a low chance your child will be homosexual, but if the skewing of the chromosomes is higher, the probability is higher, etc.. (assuming the research holds some truth) (again, as the OP said, this is probably correlation, not causation)

    Basically, it isn't about birth defects, mistakes, or "disorders" with some negative connotation; it's just PROBABILITY, and things with low probability in biology tend to be given names that are generally READ as negative, but do not imply anything negative in themselves.

    Also, I find the original post quite interesting.. going to read some more now lol.
     
  9. RaeofLite

    Full Member

    Joined:
    Apr 7, 2009
    Messages:
    1,344
    Likes Received:
    0
    Location:
    BC, Canada
    I've always wondered if homosexuality is the result from nature wanting to make sure humans don't overpopulate? By having same sex couples not able to naturally reproduce, the idea was maybe that humans wouldn't? Even though we obviously have overpopulated and gay couples do have children by other means in some cases.

    I don't think it's a mistake, but maybe this is nature's way of saying: "Ok, don't f*** with the planet and overpopulate, so you special people can be attracted to the same sex so this doesn't happen."
     
  10. Stephen505

    Regular Member

    Joined:
    Dec 29, 2009
    Messages:
    26
    Likes Received:
    0
    Location:
    Toronto, ON
    Gender:
    Male
    Sexual Orientation:
    Gay
    Out Status:
    Out to everyone
    Now to talk about the actual topic lol... Just skimmed through that site..

    Number 4 was a bit misleading! Those percentages aren't really related to the skewing. It just meant that in the mothers of homosexual men, 13% of the mothers had "high" skewing, and only 4% of the mothers of heterosexual men had "high" skewing. When they did this they just defined a cut-off point of what would be called "high".. the percentages don't depict "how much" skewing there was.

    But ya, this is a pretty hard thing to analyze.. I don't know exactly how they analyzed their data and probabilities and averages, but really.. there's a chance that some of the kids weren't even completely sure of their orientation at the time. The number of children the people have would mess with the results (though I think they took that into consideration and it helped the results [ie/ part where mothers of two homosexuals had higher rate of "high" skewing and vice versa]). Basically, there's a lot of probabilities and randomness within the probabilities that they're measuring lol...

    Anyways, assuming there were no major flaws in the data collection, it is seen that "high" skewing occurs in both mothers, so it would definitely not be causation (little joke: unless the "heterosexual" sons of the mothers with "high" skewing didn't know they were gay, in which case this can be used as a gay tester! lol....). Only 13% of the mothers of openly gay sons exhibited the "high skewing". Though, that isn't to say that the other 86% had low skewing. There's a big range that they just left out. Would have been nice if it were like: 13% high, 57% medium, 30% low... lol.. which is probably the case.

    Overall, I'd like to trust these guys and say that 13% vs 4% is a fairly large difference when looking for correlations (especially when they went into the mothers with multiple sons with even greater differences) and maybe the skewing is ONE factor that affects sexuality.

    lol.. to get really nice results, instead of taking a sample of mothers, they should choose one mother with high skewing and one with low then make them have lots of babies and see how many turn out gay or not! ..joking.... but that would help, technically.. eliminate the other variable.. I'll shut up now.
     
  11. Adam

    Full Member

    Joined:
    Oct 4, 2008
    Messages:
    445
    Likes Received:
    0
    I always thought this too, maybe we are just part of some evolution thing we don't understand yet.
     
  12. LostandFound

    LostandFound Guest

    I'm gay, my brother is not. Therefore this skewing is probably only one piece in an incredibly complex puzzle.
     
  13. Hoppip

    Full Member

    Joined:
    May 27, 2008
    Messages:
    838
    Likes Received:
    0
    Location:
    Johto
    Oops. Sorry about that, my bad. x]
     
  14. peaceloverugby

    Regular Member

    Joined:
    Dec 29, 2009
    Messages:
    14
    Likes Received:
    0
    Location:
    St. Louis, MO
    Gender:
    Male
    Sexual Orientation:
    Gay
    Out Status:
    A few people
    To be honest, I only read the first post, maybe someone else explained this but I have a question: How can a mother have one gay son, and one straight son? Seems to me if this skew was true, either all of her sons would be straight, or all of them would be gay.
     
  15. Stephen505

    Regular Member

    Joined:
    Dec 29, 2009
    Messages:
    26
    Likes Received:
    0
    Location:
    Toronto, ON
    Gender:
    Male
    Sexual Orientation:
    Gay
    Out Status:
    Out to everyone
    Short answer: This skew thing is not a "cause of homosexuality", but there is a relation (from the research). It just deals with probabilities of one factor that contributes to it.

    "If this skew was true", it would mean that having a gay son means you have a high probability of the next being gay (assuming you look at JUST the skewing factor). Really, this research doesn't mean much on its own, and can't be used to "extrapolate" or infer anything. It's just a correlation between two things. ...in my mind, at least.
     
  16. kettleoffish

    Full Member

    Joined:
    Feb 20, 2009
    Messages:
    891
    Likes Received:
    0
    Location:
    Scotland
    this is also true of me. My only full sibling (both parents the same) is my straight brother. However, I have a half sister (on my dad's side, with another mother) who is gay, as well as another half sister (with a different mother from me and my other half sister) who is straight, and a half brother (with yet another different mother) who I have never met so I don't know his orientation.

    Yes, my dad must have got around.
     
  17. mattypants

    Full Member

    Joined:
    Oct 17, 2008
    Messages:
    718
    Likes Received:
    0
    Location:
    Los Angeles
    i always thought that too
    as if the environment subtly told the mom's bodies there are enough people, so go ahead and make ones that wont lead to more children
    cause you know how they say changes in environment can stimulate change :rolleyes:
     
  18. bkwrm175

    Regular Member

    Joined:
    Dec 18, 2009
    Messages:
    20
    Likes Received:
    0
    Location:
    Lethbridge
    Gender:
    Male
    Sexual Orientation:
    Gay
    Out Status:
    Out to everyone
    I personally think this is really interesting. I don't have any issues with people saying that there is something different with homosexuals - there is.

    I have mixed feelings with how much they study body chemistry and causes of homosexuality. On one side, more evidence that it isn't a choice is always nice, and I find it REALLY interesting, but the thought that someone might come out with a 'vaccine' or 'cure' scares the crap out of me. It's a variation, not a sickness.
     
  19. paint

    Full Member

    Joined:
    Mar 26, 2008
    Messages:
    0
    Likes Received:
    0
    Location:
    Clear Lake City, TX
    It occurs in creatures other than humans though.
     
  20. Meropspusillus

    Full Member

    Joined:
    Dec 7, 2008
    Messages:
    597
    Likes Received:
    0
    Location:
    New Mexico
    It's nice to think that way, but there isn't really a sentient "nature" wanting to make sure humans don't overpopulate, or anything doesn't overpopulate for that reason.

    Overpopulation is a common part of many life cycles on earth, and when there are too many of an anything, it's resolved when most of them just die due to lack of resources.

    I'm sure homosexuality was evolved and is beneficial in some way to the survival of the species (or more likely the family of the homosexual, kin selection makes more sense than "species selection"), or at least was at some point, (it could be a evolutionary relic).

    Also, I use parentheses too much.